Endocrine Abstracts

Background: Quality of life (QoL) has become a useful outcome in recent studies among different specialties. In Cushing’s syndrome, elevated cortisol levels result in a decreased QoL, the cause for this impairment being multifactorial. More studies are necessary to find modifiable factors where doctors could intervene and thus improve QoL.Objective: To evaluate QoL in a group of Romanian patients with Cushing’s syndrome. Design: We performed a ...

Introduction: Meningiomas, already one of the most frequent types of primary central nervous system tumors, have been increasing in incidence in the past decade. Considering their location and histologic particularities, radiation therapy (RT), alone or in combination with neurosurgery, is often necessary and can have a negative impact on adjacent structures such as the pituitary gland. More studies investigating the endocrinologic disturbances in this pathology are necessary ...

Introduction: Although calcifications are a relatively common finding on a thyroid ultrasound, present in both benign and malign lesions, osseous metaplasia (OM) is a peculiar discovery, with only a few described cases in literature so far. Common pathophysiological explanations include abnormalities of bone morphogenetic protein family members and basic fibroblast growth factor. Most of the case reports are presenting OM in association with malign lesions, often with papillar...

Background: Despite current efforts in trying to accurately identify determinants of impaired quality of life (QoL) in acromegalic patients, studies on this topic are still conflicting and more research is needed in order to improve the well-being of these patients.Methods: We conducted a cross-sectional study, administering two standardized questionnaires (AcroQol and EuroQol-5D) to 38 acromegalic patients and examined ...

Introduction: Cushing’s syndrome (CS) is associated with a plethora of metabolic consequences. Current literature regarding the impact of different aetiologies on metabolic complications is scarce, and results are inconsistent. More studies are needed to validate previous findings.Aim and methods: In order to compare the outcomes of pituitary and adrenal CS, we conducted an observational retrospective study, investigating the medical records of 72 p...